Stock ECU's and large changes to throttle body sizing

I have been asked on a Toyota Supra MKIV twin turbo forum whether a stock Toyota ecu will be happy if the owner fits a big Q45 throttle body and large volume plenum to a basically stock engine and a stock ecu. My feelings are there will then be a big disparity between throttle position sensor voltages and MAP sensor voltages that the stock ecu may be incapable of resolving. May I ask your thoughts even though this is not MOTEC related, although, as usual, I have often advised forum members of the superb support and tuner base fitting a MOTEC would bring
Thanks.
